他们的研究成果以 “LYMPHOMA STAT6 mutations compensate for CREBBP mutations and hyperactivate IL4/STAT6/RRAGD/mTOR signaling in follicular lymphoma” ...

Overall, our results suggest that DE 354 miRNAs, including miR-4261, miR-126-5p, miR-411-5p, miR-612, miR-504-3p, and miR-3687, and mRNA of the ATN1, GEMIN4, EFNA5, CSMD2, CREBBP, ATXN1, and B3GNT2 ...

肿瘤类器官在淋巴瘤精准医疗方面又有新突破！来自斯坦福大学和加州大学的科研人员在《Cell stem cell》（影响因子IF=23.90）发表研究论文 ...

The genetic basis of most traits is highly polygenic and dominated by non-coding alleles. It is widely assumed that such alleles exert small regulatory effects on the expression of cis-linked genes.

Rare diseases (RDs), more than 80% of which have a genetic origin, collectively affect approximately 350 million people worldwide. Progress in next-generation sequencing technology has both greatly ...

肿瘤类器官在淋巴瘤精准医疗方面又有新突破！来自斯坦福大学和加州大学的科研人员在《Cell stem cell》（影响因子IF=23.90）发表研究论文[1]指出 ...

Impact of loss of PRLHR on aneuploidy and initiation of bladder cancer. PPARG protein expression in advanced urothelial carcinoma and selection for response to FX-909, a first-in-class PPARG-targeting ...

4例病例显示出意义未知的非频发融合，包括FCHSD2::CREBBP、IL12RB2::ACTB、NFIC::RBBP4 / ZNF266::BID以及ABL1::DCC。 128例患者有DNA测序结果。其中，1例患者的8个基因出现突变或拷贝数变异（CNV，包括基因缺失、基因部分缺失或扩增），另外1例患者的5个基因、2例患者的4个 ...

ABSTRACT Introduction: The treatment of elderly multiple myeloma (MM) patients with autologous stem cell transplantation (ASCT) is a controversial procedure. Most clinical trials evaluating the safety ...

Chemical Genomics Centre, Max Planck Institute of Molecular Physiology, Dortmund 44227, Germany Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund 44227, Germany ...