HSC和MPP表型：HSCs占CD34+祖细胞的1%，具有特定的表型，包括CD90+、CD38-、CD34bright、CD13+、CD4-、CD33-、CD123-、HLA-DR+等。MPPs与HSCs表 ...

此外，纳米刀片与甘露糖偶联的 rAAV6（K3E5）介导的敲入对非常不成熟的 CD34 + CD38 low CD90 + 干细胞群体有轻微偏好 。综上，rAAV6 与 3E5 甘露糖当量在衣壳赖氨酸残基上偶联并结合纳米刀片，可在 CD34 + 细胞中实现等效敲入水平，并显著降低细胞死亡率。 六、甘露糖 ...

引言在人类基因组计划完成的二十年后，研究人员发现：我们就像拿着字典却不懂语法的孩童，面对37万亿个细胞组成的"人体宇宙"，依然读不懂生命真正的对话方式。单细胞测序技术曾让我们惊喜地发现，一滴血里藏着各种免疫细胞的"职业分工"，一片癌组织中潜伏着上各种基因变异的"叛乱分子"。但当显微镜放大到分子级别，70%的基 ...

Johnson & Johnson is dropping a partnership with Genmab centered around a CD38 monoclonal antibody, prompting the latter company to discontinue development of the program. Back in 2019 ...

Johnson & Johnson has decided that it will not exercise its option to receive a worldwide license to develop, manufacture and commercialize HexaBody-CD38 Genmab will not pursue further clinical ...

While the initial HexaBody-CD38 clinical data is promising and showed robust clinical efficacy, following a thorough evaluation of the data, the market landscape, and Genmab’s rigorous portfolio ...

Early measurable residual disease clearance is linked to better outcomes in acute myeloid leukemia, study suggests.

常用的B细胞标记物包括CD19、CD20和CD45R（B220）。未成熟B细胞表达CD19、CD20、CD34、CD38和CD45R，但不表达IgM；成熟B细胞则主要通过IgM和CD19标识。活化B细胞表达CD30，血浆B细胞表达CD78，记忆B细胞通过CD20和CD40标记。 T淋巴细胞（T细胞）是由骨髓中的造血干细胞在胸腺 ...

This revised study provides valuable information on the single nucleus RNA sequencing transcriptome, pathways, and cell types in pig skeletal muscle in response to conjugated linoleic acid (CLA) ...