The mechanism of action of bupropion is unknown, as is the case with other antidepressants. However, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms.

Medically reviewed by Mary Choy, PharmD Wellbutrin is sometimes prescribed for ADHD. While not typically the initial medication of choice, it may be recommended if your current medication is not ...

Objectives. To identify predictors of smoking abstinence at the end of medication use that could assist in the optimal use of a sustained-release (SR) form of bupropion for treating cigarette smokers.