For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the ...

The blood-brain barrier has confounded the development ... charge and lipid solubility of a compound to facilitate BBB transport. The apical sides of endothelial cells, which face the blood ...

is a passive impermeable barrier that segregates blood and brain interstitial fluid has given way to the concept that the BBB is a dynamic conduit for transport between the blood and the brain for ...

Financial writer recommends Voyager Therapeutics, Inc. for high-risk investors due to promising preclinical Alzheimer's ...

ABL Bio’s first-in-class bispecific antibodies for Parkinson’s disease combine unprecedented blood–brain barrier penetration with a robust mechanism of action for improved therapeutic efficacy.

The paper is titled "Intravenous administration of blood-brain barrier-crossing conjugates facilitate biomacromolecule transport into central nervous system." The blood-brain barrier is a natural ...

The BCC10 compound uses transcytosis to prompt cells in the blood-brain barrier to transport the drugs across the barrier from within, researchers said. The treatment was well-tolerated in the ...

The blood-brain barrier (BBB) is a cellular fortress that regulates what comes in and goes out of the brain. It ensures that the brain has access to key nutrients while protecting it from pathogens ...

showing they can cross the blood-brain barrier, and the amounts of the tiny plastic bits inside our bodies appear to be increasing at a rate that reflects the increasing amount of global plastic ...

Rice University chemist and director of the university’s Synthesis X Center Han Xiao and cancer biologist Dihua Yu of The University of Texas MD Anderson Cancer Center have received a three-year, $1.5 ...