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Nature Medicine | 九个月后的基因叛变:多组学解析CAR-T细胞"黑化"之路
2月21日《自然医学》披露的特殊病例引发全球关注:一位接受CAR-T治疗的多发性骨髓瘤患者,竟在9个月后遭遇外周T细胞淋巴瘤的突袭。这场抗癌疗法引发的"细胞叛变",揭开了现代免疫治疗最隐秘的基因暗战。
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