Like retrosynthesis, bioretrosynthesis is a design process that potentially simplifies biosynthetic pathway strategic design. Unlike retrosynthesis, bioretrosynthesis is also a practical ...

The biosynthetic pathways leading to such bonds ... Redox transformations can be followed by a nonredox process that establishes key connections en route to a complex target.

Addressing these process-model mismatches (PMMs) is a significant challenge in controlling biosynthetic processes.