The renin–angiotensin system (RAS) is involved in the regulation of vasoconstriction, fluid homeostasis, cell growth, fibrosis, inflammation, and oxidative stress. In recent years, unprecedented ...

Qureight Ltd, a Core Imaging Laboratory developing deep-learning image analytics, and Vicore Pharma, a clinical-stage biopharmaceutical company unlocking the potential of angiotensin II type 2 ...

Although the underlying mechanisms and mediators of arterial stiffness are not well understood, accumulating evidence supports the role of insulin resistance and endothelial dysfunction. The local ...

Nonetheless, supportive of our findings is the report of interaction between rs5186 genotype and gender on the renal hemodynamic response to angiotensin II. 104 Further testing with larger studies ...

Finally, the dissolution was frozen for 2 days and then lyophilized. X-ray photoelectron spectroscopy (XPS) analyses were conducted using a scanning XPS microprobe (PHI 5000 VersaProbe II) in an ...

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We have shown that the brain CD38 expression and enzymatic activity are increased in the setting of hypertension (HTN) including spontaneously hypertensive stroke prone rat and angiotensin-II (Ang-II) ...

The mechanism is thought to involve reduction in vascular nitric oxide by increased ... The vascular response to angiotensin I was blunted in the presence of aldosterone blockade, suggesting that less ...

This is an important study providing convincing evidence that increased blood pressure variability impairs myogenic tone and diminishes baroreceptor reflex. The study also provides evidence that blood ...

HF is associated with increased activity of the renin-angiotensin-aldosterone system, increased secretion of vasoconstrictive molecules, and increased sympathetic nervous system activity.