In Alzheimer's disease (AD), amyloid β-protein (Aβ ... proteins were unusually rich in highly ordered, β-pleated sheet structure, providing an apparent explanation for their long-known property ...

Panelists discuss how amyloid-targeting therapies for Alzheimer disease represent a breakthrough drug class that works by binding to and removing beta-amyloid plaques through various mechanisms ...

The protein amyloid beta, which occurs naturally in the brain ... They then used 3D light-sheet microscopy to study plaque formation throughout the brain, providing a complete picture of amyloid ...