POMs are a class of inorganic metal-oxygen cluster compounds with broad-spectrum antitumor potential. However, their strong hydrophilicity and poor ...

CUO-Recherche, Centre de recherche du CHU de Québec and Département d’ophtalmologie, Faculté de médecine, and Regroupement stratégique PROTEO, Université Laval, Québec, Québec G1V 0A6, Canada Centro ...

FAs are important in cellular processes such as membrane structure, energy storage, and signaling. However, challenges remain ...

This article presents a method for preparing stable and reproducible fatty acid (FA) stock solutions, which are essential for studying lipid ...

Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...

Alzheimer’s disease (AD) is a multifactorial, age-related neurological disease characterized by complex pathophysiological dynamics taking place at multiple biological levels, including molecular, ...

Given these similarities in channel topology and components, how is it that KCNQ1, hERG, and SCN5A perform such distinct functions, and produce phenotypically distinct forms of LQTS? To explore this ...

School of Automobile and Transportation Engineering, Guangdong Polytechnic Normal University, Guangzhou 510450, China Guangdong Provincial Key Laboratory for Processing and Forming of Advanced ...

AlphaFold24 and molecular-dynamics-based refinement. The structure consists of a large globular N-terminal domain and an approximately 61-nm-long continuous amphipathic β-sheet that wraps around ...