Most DUBs catalyse a proteolytic reaction between a Lys ɛ-amino group and a carboxyl group corresponding to the C terminus of ubiquitin. The Cys protease DUB families (USPs, UCHs, OTUs and ...

Sarah Vine and Andrew Pierce bring their own no-holds-barred opinions, insights and reaction (clue is in the title) to the biggest stories of the week. New episodes every Wednesday, wherever you ...

Salmonellae are globally important Gram-negative bacterial pathogens that infect a range of hosts and cause several diseases, including gastroenteritis and typhoid fever. Orally ingested bacteria ...

The inactivation of programmed cell death has profound effects not only on the development but also on the overall integrity of multicellular organisms. Beside developmental abnormalities, it may lead ...

A change is called irreversible if it cannot be changed back again. Many chemical reactions are irreversible. In a chemical reaction, new materials are always formed. Sometimes these new materials ...

All fatty acids consist of a carbon chain that terminates in a carboxylic acid functional group ... These intermediates enter fatty acid synthase (FAS), where four reactions take place; condensation, ...