Melanoma is a type of cancer that starts in cells called melanocytes. These are found in the skin, the layer of tissue lining some parts of your body (mucous membrane) and the eye. This section is ...

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Subungual melanoma is rare but serious. Unlike other skin cancers, subungual melanoma isn’t linked to sun exposure. It’s most likely to develop in your big toe, thumb or index finger.

Specifically, David had developed subungual melanoma — a rare and aggressive form of skin cancer that develops under the nail. 'It’s awful to hear the words melanoma,' said Kelly. 'I first ...

(A) HMB-45 (−), ×200. (B) P16 (−), ×200. (C) Cyclin D1 (+), ×200. (D) Ki-67 (about 20%, +), ×200. imageFigure 1 (A) A pinkish nodule with an ulcerated surface on the inner of the left leg. (B) ...

Nail psoriasis sometimes causes too much keratin to grow under the nail. This overgrowth is called subungual hyperkeratosis. People with hyperkeratosis may notice a white, chalky substance under ...

Repeated long-term rubbing of the toe against the tip of the shoe may also result in the nail edge coming loose without any bleeding beneath the nail. Subungual melanoma, or malignant cancer in the ...

A biopsy taken from the nail matrix showed an increased number of melanocytes, atypia, and transepidermal invasion, features consistent with malignant melanoma (Figure 2). A surgical excision was ...

A biopsy was performed, and eight weeks later, the results revealed it was subungual melanoma, a type of acral lentiginous melanoma (ALM). "Knowing what I know, this diagnosis was music to my ears ...

A biopsy revealed devastating news — Ms Heather had melanoma, the deadliest form of skin cancer. When the disease starts under the nail it is known medically as subungual melanoma and typically ...

The treatment landscape for melanoma saw significant advancements in 2024, as highlighted by Elisa Funck-Brentano, MD, PhD, from Ambroise-Paré Hospital in Paris, France, during her presentation ...