The mechanism of action may be associated with upregulation of the IRS1/PI3K/AKT signaling pathway and inhibition of IRS1 phosphorylation. Type 2 diabetes mellitus (T2DM) is a metabolic disease with a ...

The results indicated that TA modulated the pathway of Akt/GSK-3β, which may contribute to TA-induced dopaminergic neuron protection. Fresh G. mangostana L. from Thailand were obtained from Guangzhou ...

Eosinophils play a crucial role in allergic responses, secreting cytokines and inflammatory mediators that exacerbate AR ...

The following is a summary of “Mendelian randomization of plasma proteomics identifies novel ALS-associated proteins and their GO enrichment and KEGG pathway analyses,” published in the March 2025 ...

Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA ...

Leading oncologists discuss the role of PI3K/AKT inhibitors in breast cancer treatment, highlighting INAVO120 trial data, the importance of early genetic testing, and side-effect management.

In amongst a clutch of discontinued phase 3 programmes in Roche's fourth-quarter results update was the news that it has stopped a study of AKT inhibitor ipatasertib as a treatment for first-line ...

President Donald Trump detailed how the U.S. plans to assert crypto leadership leadership during a first-ever White House ...

Following injury, many organs are capable of rapid regeneration of necrotic tissue to regain normal function. In contrast, ...

In Today's Scripture Reading: Clean and unclean food; the Law of the tithe; dedication of the firstborn; three feasts to be observed; judges and justice The prosperity of Israel in the promised land ...