In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

CBL-514, the world's first investigational drug for large-area localized fat reduction, has demonstrated significant efficacy in its second and the last Phase 2b study (CBL-0205) before Phase 3.54.2% ...

Furthermore, HFD provokes uncontrolled basal lipolysis and promotes unnecessary release of FFAs, causing imbalanced immune responses in adipose tissue. Also, when lipid storage capacity of adipocytes ...

CBL-514, the world's first investigational drug for large-area localized fat reduction, has demonstrated significant efficacy in its second and the last Phase 2b ...

One of the manifestations of adiposopathy is a relative increase of intra-adipocyte lipolysis over that of intra-adipocyte lipogenesis, leading to a net release of FFAs, insulin resistance and ...

Fasting induces lipolysis in adipocytes and gluconeogenesis in the liver. AQP7 mRNA levels are elevated by the decrease of insulin and adrenergic receptor activation causes the AQP7 protein to ...

Postpartum insulin supplementation significantly reduces the change of adipocyte size in obese cows, which is beneficial to buffer the intense lipolysis and adipose tissue remodeling caused by more ...

Fat metabolism is a fascinating process and essential for human survival. It involves the digestion, absorption, transportation and utilization of lipids as a source of energy or as an energy reserve.