Intercellular adhesion can be mediated by adherens junctions, tight junctions and desmosomes, whereas cells can interact with extracellular matrix molecules through focal adhesions ...

β-catenin is an integral part of adherens junctions and a central component of canonical Wnt signaling. Here, the authors addressed the role of β-catenin in fibroblasts for the development of SSc ...

"Our work also shows the importance of force transmission to be regulated by the ability of epithelial tissues to interact with each other through adherens junctions with potential in ...

In addition, abnormal expression of cell-to-cell adhesion proteins at the level of tight junctions, adherens junctions and desmosomes was shown. Furthermore, patients were characterised by the ...

The paracellular route is almost entirely sealed by tight junctions (TJ) and adherens junctions (AJ). TJs comprise complexes of transmembrane proteins including occludin, claudins and junctional ...

which are complex syndromes with an associated ARVD/C phenotype, have been identified as plakoglobin and desmoplakin, respectively. These genes encode proteins which are important in the cardiac ...

In normal cells, Kbu marks were linked to adherens junctions and ion transport. In contrast, in CRC cells, they were associated with mesenchymal proliferation and apoptotic signaling, reflecting ...

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Mechanobiology Institute Singapore, National University of Singapore, Singapore 117411, Singapore ...

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