The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme, becomes activated by G-protein molecules associated with the adrenergic receptor. Adenylyl cyclase creates ...
Our strain collection includes strains expressing each of the 10 mammalian adenylyl cyclases as well as wild-type and mutationally-activated forms of the human GNAS Gα. A recent screen of ~125,000 ...
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