Adenosine, a pervasive autacoid, can mediate both pro- and anti-inflammatory responses once released in response to inflammation or infections. In physiological conditions, the extracellular ...

New research published in Journal of Neurochemistry finds that cannabidiol (CBD) may protect against neuronal death in epilepsy by inhibiting neurotoxic reactive astrocytes, a subtype of astrocytes ...

Adenosine is an important chemical known as a nucleoside that exists naturally in all cells of the body. It is used to transfer energy within the cells by forming molecules like adenosine triphosphate ...

Namodenoson, has been also granted Orphan Drug Designation by the FDA for pancreatic cancer. The designation as an orphan drug will provide, among others, potential for market exclusivity for seven ...

This valuable study identifies a protein called adenosine deaminase-related growth factor (ADGF) as a key regulator of tip formation in the slime mold Dictyostelium discoideum. The authors ...

Scientists have made a major discovery about ADAR1—a protein that controls RNA-induced immune responses—paving ...

A research team led by Yang Gao from Rice University has made significant strides in understanding the molecular mechanisms of ADAR1, a protein that modulates ribonucleic acid (RNA) induced immune ...

These results have led to interest in the diet for treating conditions such as Alzheimer’s disease, depression and schizophrenia. Evidence points to the neuromodulator adenosine as a key mechanism ...

A research team has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses. Their findings could open new pathways for ...

This paper provides a valuable contribution to our understanding of how adenosine acts as a signal of nutrient insufficiency and extends this idea to suggest that adenosine is released by ...

Collaboration Revenue: There was $2.3 million of collaboration revenue for the year ended December 31, 2024, as compared to no collaboration revenue for the year ended December 31, 2023. The increase ...