Laboratory of Organic Chemistry for Drug Development and Medical Research Laboratories, Department of Pharmaceutical Sciences, Kitasato University, Tokyo 108-8641, Japan ...

Salmonellae are globally important Gram-negative bacterial pathogens that infect a range of hosts and cause several diseases, including gastroenteritis and typhoid fever. Orally ingested bacteria ...

AG, acyl ghreline; BBB, blood brain barrier ... for the maintenance of blood glucose homeostasis during severe calorie restriction in mice (Zhao et al., 2010). Thus, up-regulation in ghrelin synthesis ...

Another interactor of TRPV2 is Acyl-CoA binding domain containing 3 (ACBD3), which mediates the TRPV2–PKA interaction and subsequent PKA-mediated phosphorylation (281). ACBD3 is involved in the ...

The development of methods for conversion and utilization of amides has attracted much attention in organic synthesis and drug discovery. Herein, the authors report a divergent alkynylative ...

The solution turns brown. This brown colour is the displaced bromine. The chlorine has gone to form sodium chloride.