This study provides compelling evidence that kinesin's stepping mechanism is governed by strain-induced conformational changes in its nucleotide-binding pockets. Using pre-steady state kinetics and ...

This elemental event, which is part of a cycle driven by ATP hydrolysis, is known as the 'power-stroke'. Although the swinging cross bridge was first proposed 30 years ago and is supported by an ...

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...

ATP (adenosine triphosphate) is the energy-carrying molecule used in cells because it can release energy very quickly. Energy is released from ATP when the end phosphate is removed. Once ATP has ...