Canadian pension fund investment manager Caisse de dépôt et placement du Québec (CDPQ) has agreed to buy Quebec-based renewables developer Innergex Renewable Energy for CA$10bn ($7bn). Innergex ...

potentially through the activation of Adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK) phosphorylation (Zhang et al., 2020). Thirdly, berberine exhibits potent anti-inflammatory ...

Here, we found that inhibition of AMPK occurs during naïve transition with two conventional inhibitors of the MEK1 and GSK3β pathways. The accumulation of glycogen due to iGSK3β is responsible for ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cable bacteria are centimeter-long ...

Mammalian AMP-activated protein kinase (AMPK) was discovered as a protein kinase that switches off lipid synthesis. The yeast orthologue, the SNF1 complex, was discovered in screens for mutations ...

The provided evidence is solid with state-of-the-art genetic analysis of large human cohorts followed by a comprehensive analysis of a mouse SLC39A5 knockout mutant, establishing that SLC39A5 plays a ...

The melanoma-associated antigen family A (MAGEA) antigens are expressed in a wide variety of malignant tumors but not in adult somatic cells, rendering them attractive targets for cancer immunotherapy ...

AMP-activated protein kinase (AMPK), a key metabolic regulator, plays an essential role in the maintenance of energy balance in response to stress. Tuberculosis (TB), primarily caused by the pathogen ...