Canadian pension fund investment manager Caisse de dépôt et placement du Québec (CDPQ) has agreed to buy Quebec-based renewables developer Innergex Renewable Energy for CA$10bn ($7bn). Innergex ...

In a model of renal aging and injury induced by D-galactose (D-gal), hyperoside exhibited significant renal protective effects. The underlying mechanism appears to be associated with the inhibition of ...

potentially through the activation of Adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK) phosphorylation (Zhang et al., 2020). Thirdly, berberine exhibits potent anti-inflammatory ...

Here, we found that inhibition of AMPK occurs during naïve transition with two conventional inhibitors of the MEK1 and GSK3β pathways. The accumulation of glycogen due to iGSK3β is responsible for ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cable bacteria are centimeter-long ...

Here, the authors developed a cell-based screening assay for the identification of small molecule inhibitors of nonsense-mediated decay (NMD), and used it to validate KVS0001, a new small molecule ...