In Eukarya, RNA Polymerase II (Pol II) transcription is a highly regulated process, which is responsible for the transcription of all protein encoding genes. While the catalytic core of the Pol II ...

How do bacteria avoid wasteful production of unnecessary proteins when their genes are always on? The answer lies in regulating the operon. As trp levels increase, trp binds to trpR, causing a ...

If our genes are so similar, what really makes a eukaryote different from a prokaryote, or a human from E. coli? The answer lies in the difference in gene expression and regulation used.

Aging cells with weakened gene regulation spuriously transcribe RNAs, but their impact on health and longevity still needs to be examined. Kamal is a freelance science journalist based in the UK with ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in ...

“The novelty and merit of this work is that the authors demonstrate, for the first time, that [telomere transcription] occurs in response to physical exercise in a physiological system—human muscle,” ...

Sanofi has returned to Nurix Therapeutics for another autoimmune candidate, paying $15 million and committing up to $465 ...

Nurix DEL-AI drug discovery engine generated a drug discovery program to this previously undruggable target Nurix received a $15 million license extension fee from Sanofi under its 2019 collaboration ...

Gene regulation underpins nearly every biological process—from cell development to responses to environmental changes, and understanding it can provide insights into cancer and other diseases.