Like retrosynthesis, bioretrosynthesis is a design process that potentially simplifies biosynthetic pathway strategic design. Unlike retrosynthesis, bioretrosynthesis is also a practical ...

The biosynthetic pathways leading to such bonds ... Redox transformations can be followed by a nonredox process that establishes key connections en route to a complex target.

Addressing these process-model mismatches (PMMs) is a significant challenge in controlling biosynthetic processes. Fortunately, a research team led by doctoral student Tomoki Ohkubo from the ...

Protein biosynthesis—the process whereby cells produce protein molecules, which are essential for life and growth—is a highly complex and strictly regulated affair. An interdisciplinary team ...