IGF-binding protein (IGFBP)-2 is the principal IGFBP produced by white adipocytes during adipogenesis, and circulating levels are reduced in obesity. Overexpression of IGFBP-2 in transgenic mice ...

CellGenTech, headquartered in Chiba, Japan, is pioneering the use of a new cell type—adipocytes suitable for gene therapy—for ex vivo applications in a range of diseases caused by single-gene ...

Their findings are published in Nature Biotechnology in an article titled, “Implantation of engineered adipocytes suppresses tumor progression in cancer models.” The team of researchers used ...