Cancer stem cells, characterized with self-renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription ...

Translation of human pluripotent stem cells into cell therapies will require the development of standardized tests for product consistency, stability, tumorigenicity, toxicity and immunogenicity.

We then reveal gene expression and epigenetic profi les of various human iPS cells genome-widely. By combining these data, we try to squeeze molecular markers thatrepresent pluripotency and ...

Cancer stem cells, characterized with self-renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription ...