引言在人体这个精密运转的宇宙中，肝脏堪称最神秘的"化学工厂"——它能同时执行解毒、代谢、储存等多项功能，甚至在切除70%后仍能完全再生。但你是否想过，这个1.5公斤的器官如何实现精准分区管理？为什么同样的药物剂量，有人轻松代谢，有人却中毒身亡？3月1 ...

Researchers have found that stellate cells – known for their role in liver fibrosis – play a key role in protecting and ...

New research suggests restoring stellate cells to their healthy and protective state could simultaneously reduce liver scarring and improve liver function.

2025年3月3日，丹麦大学生物化学与分子生物学系Kim Ravnskjaer团队在Cell Metabolism发表“Hepatic stellate cells regulate liver fatty acid utilization via ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Hepatic stellate cells reside between the hepatocytes and small blood vessels in the liver. They are characterised by the presence of lipid droplets and thin protrusions extending around the blood ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate cells. Lhx2 was found to simultaneously promote liver regeneration and ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

Inflammation and cell death are key triggers of hepatic fibrogenesis in NAFLD, with hepatic stellate cells (HSCs) playing a ...