Soluble oligomeric assemblies of amyloidogenic proteins are increasingly thought to initiate disease-specific cytopathology and subsequent symptoms. Larger deposits, such as compacted Aβ plaques ...

The tools and tricks for studying membrane proteins are different from those used for soluble proteins, he says, but the strategy is the same: working on all aspects of the process. “The key to ...

We wanted to get these proteins out of the cell membrane, so we redesigned them as hyperstable, soluble analogues, which look like membrane proteins but are much easier to work with." Casper ...

Neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS (amyotrophic lateral sclerosis) are debilitating conditions ...

Amyotrophic lateral sclerosis (ALS) is a relatively rare but very serious disease of the nervous system. A cure is not yet ...

"We wanted to get these proteins out of the cell membrane, so we redesigned them as hyperstable, soluble analogs, which look ...

While a comprehensive cure-all to these neurological conditions is unlikely, scientists are making headway into understanding their fundamental characteristics with the hope of preventing or ...

Nuclera, the biotechnology company accelerating protein expression and optimization through its benchtop eProtein Discovery™ system, today announced the addition of a new membrane protein workflow to ...

and certain hormones like insulin and enzymes are all examples of globular proteins. They have their spiral chains folded intro spherical shapes and are generally soluble in water. However the ...