Purpose: The pharmacology, pharmacokinetics, clinical efficacy, and safety of rasagiline are reviewed. Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and ...
ADAGIO is a delayed-start trial designed to test whether the monoamine oxidase type B (MAO-B) inhibitor rasagiline can act as a disease-modifying medication in PD. 2 1,176 patients with early ...
Coadministration of rasagiline and ciprofloxacin (a CYP1A2 inhibitor) increases the AUC of rasagiline by 83%. [47] Thus, potent CYP1A2 inhibitors (e.g., ci-metidine, ciprofloxacin, fluvoxamine ...
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