New TLC stars Jay Manuel and Pamela Chavez were born with Osteogenesis Imperfecta type 3, also known as brittle bone disease.

TLC’s Jay & Pamela introduced many viewers for the first time to osteogenesis imperfecta type 3, the super-rare genetic ...

For decades, the rare bone condition osteogenesis imperfecta has been diagnosed on a spectrum, from mild to lethal. New ...

Osteogenesis imperfecta (OI), also known as brittle bone disease, is a rare genetic disease affecting the connective tissue and bones. In this disease, bones become extremely fragile and break or ...

Growth, bone density, histology and fracture number are important outcome parameters, but are not simple to measure accurately and reproducibly in children with severe OI. For example, using ...

Osteogenesis imperfecta (OI) is an inherited (genetic) bone disorder that is present at birth. It is also known as brittle bone disease. A child born with OI may have soft bones that break ...

Jay Manuel, 28, and Pamela Chavez, 30, were both born with osteogenesis imperfecta type 3 — often called brittle bone disease ...

Even if you don’t have traditional cable, you can still watch the “Jay & Pamela” on TLC for free using free trials from ...

In a clip from the Jay & Pamela premiere, a doctor urged the pair to get more calcium in their diets. “With osteogenesis ...

You have full access to this article via your institution. In human JEB, besides mutations of the laminin-5 gene, mutations in type XVII collagen and α6β4-integrin genes have been reported 25.