TNFRSF11A encodes the receptor activator of NFκB (RANK), which is critical for normal osteoclast formation; genetic variants in this gene result in familial expansile osteolysis, a Paget-disease ...

To identify novel bone remodeling factors and related mechanisms involved in both osteoclast and osteoblast differentiation, a team of researchers led by Professor Tomoki Nakashima from the ...