In addition to cell-cycle regulation, mTOR plays a role in muscle hypertrophy following increased use through the growth factor IGF-1 and tumor suppressor PTEN. Blocking mTOR with drugs like rapamycin ...

Key changes include reduced activity of mTOR, a metabolic regulator ... and occur within the unique three-dimensional structure of tumor spheroids, shedding light on the interactions within ...

mTOR, a nutrient sensor, exhibits increased activity in aging and cancer, promoting tumor growth and synchronously regulating protein synthesis and cell proliferation with circadian rhythms.

However, when a tumor develops in the pituitary gland ... Furthermore, research into targeted therapies, such as inhibitors ...

The biomarker analysis found patients with certain mutations in the PI3K/AKT/mTOR pathway and MAPK pathway may be resistant to Truqap.

The drug blocks the activity of a protein known as mammalian target of rapamycin (mTOR), which promotes proliferation through the activation of proteins such as S6 kinase. Although the mTOR ...