【导读】帕博西尼（Palbociclib）是一种CDK4/6抑制剂，在治疗HR+乳腺癌中发挥着至关重要的作用。然而，palbociclib的耐药性是一个值得进一步研究的重大问题。团队的研究发现，TMEM45A是palbociclib耐药性的潜在驱动因 ...

相关研究结果于2025年1月1日在线发表在Nature期刊上，论文标题为“Dysregulation of mTOR signalling is a converging mechanism in lissencephaly”。 论文共同通讯作者 ...

A study led by Dr. Peter Canoll's lab, in collaboration with researchers at Columbia University Irving Medical Center, ...

Adding lanreotide to everolimus significantly prolonged progression-free survival compared with everolimus alone in patients ...

Seventeen tumor samples from 14 patients with SDH-deficient GIST underwent NGS. Mutational load was low, although three patients (21%) displayed molecular events in relapse samples leading to ...

“Studies are currently underway to use this equipment in follow-up research, where we aim to investigate how tumor cells interact with neuronal structures at a deeper level,” said Dr. Canoll. The ...

In a nutshell A common desert plant called Artemisia herba-alba contains compounds that can effectively kill colorectal ...