Far from being passive repositories of encoded information and simple intermediates in the pathway from gene to protein, mRNA molecules have different ... diseases whose expression may depend ...

Advancements in mRNA vaccine technology are reshaping medicine, addressing challenges and expanding applications from ...

Three Johns Hopkins experts discuss the potential of mRNA-powered therapeutics to produce lifesaving treatments and cures for ...

"When we started this coculture for a different purpose ... imaging analysis and mouse-specific gene expression analysis, the ...

Specific DOPE-Cx derivatives, such as DOPE-C8, demonstrated significantly higher mRNA expression levels in ... applicability of DOPE-Cx lipids across different tissues and administration routes.

The study is useful for advancing spatial transcriptomics through its novel regression-based linear model (glmSMA) that integrates single-cell RNA-seq with spatial reference atlases, though its ...

mRNA can be employed to reprogram cells into different cell types, a process known as cellular reprogramming ... The ability to harness the power of mRNA to modulate gene expression and produce ...

Wang and her team were interested in synthesizing different kinds of RNA, which is normally in a linear form ... When the team tested this in a mouse model, they found that the branched mRNA led to a ...

One concern that has previously been raised about mRNA vaccines is that short-term antigen expression might result in weak memory responses. [131] Furthermore, it remained unclear how a vaccinated ...

When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA). This process takes place in the nucleus and occurs in a series of stages. The two ...