In this particular study, treatment-related mortality occurred in 5.3% and 1.6% of patients receiving irinotecan weekly and every three weeks, respectively. Determining a patient's genotype status ...

Frontline treatment with Tevimbra plus irinotecan, paclitaxel, oxaliplatin and 5-FU/leucovorin had promising efficacy and ...

A recent phase III randomized trial has failed to demonstrate an improvement in disease-free survival with the addition of irinotecan to 5-fluorouracil and folinic acid as adjuvant treatment for ...

NALRIFOX showed numerically better overall survival vs FOLFIRINOX as frontline treatment in PDAC, per real-world analysis ...

SIL-204 showed synergistic efficacy with 5-fluorouracil, irinotecan and gemcitabine in preclinical models of pancreatic cancer. ZSilexion plans Phase 2/3 trials for SIL-204 in 2026 and raised $5 ...

Silexion Therapeutics Corp. has released new preclinical results demonstrating the synergistic efficacy of its proprietary second-generation siRNA candidate, SIL-204, in combination with components of ...

Patient body fat and AI ensemble technique and the influence on false-positive rate in AI second observer for colorectal cancer detection. This is an ASCO Meeting Abstract from the 2025 ASCO ...

Find all the commercial and brand names of generic drug called Irinotecan. This is an invaluable reference resource for healthcare professionals, patients, caregivers and anyone in need of ...

Baseline geriatric vulnerabilities and QOL scores are associated with survival after chemotherapy in older adults with metastatic pancreatic cancer, researchers found.

Amgen receives US FDA approval for Lumakras in combo with Vectibix for chemorefractory KRAS G12C-mutated metastatic colorectal cancer: Thousand Oaks, California Monday, January 20 ...

XPO1 inhibition as a clinically viable strategy to enhance durability of response to KRASG12D inhibitor in pancreatic ductal adenocarcinoma.