Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

The paper S.C. Kim et al., “Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA,” PNAS, 115:13318–23, 2018. Proponents of the RNA world theory argue that ...

Researchers uncover new insights into the molecular mechanisms of ADAR1, a protein that regulates RNA-induced immune responses. Their findings could open new pathways for treating autoimmune diseases ...