EurekAlert!4d
Coumarin derivatives as inhibitors against monoamine oxidase: Structure-activity relationships and inhibitory mechanisms
Announcing a new publication for Acta Materia Medica journal. Monoamine oxidase (MAO) is a useful target in the treatment of neurodegenerative diseases and depressive disorders. Understanding the ...
eLife4d
How the layer-dependent ratio of excitatory to inhibitory cells shapes cortical coding in balanced networks
The study presents a useful computational analysis of how the ratio between excitatory and inhibitory neural numbers affects coding capacity. The authors show that increasing the proportion of ...
EurekAlert!18d
Birds have developed complex brains independently from mammals
Two studies published in the latest issue of Science, led by Dr. Fernando García-Moreno, Ikerbasque researcher at the ...
BioWorld14d
Bispecific antibody targeting KIR and ICOS restores immune balance in models of IBD
In autoimmune diseases such as inflammatory bowel disease (IBD), the function of regulatory CD8 T cells (CD8 Treg) is compromised, in part due to the expression of inhibitory KIR receptors ...