However, the mechanism by which rotaviruses enter cells is controversial, and both direct membrane penetration and endocytosis have been proposed. Recently developed molecular and biochemical ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...

After a virus attaches to its host cell, it must find some way to enter the cell. How have viruses hijacked the cell's pathways to cause infections, and how have scientists learned about ...

UMD researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines.

Small molecules can enter cells but show minimal accumulation in tumor and metastatic cells, engaging only around 10% of targets. Biologics such as monoclonal antibodies are capable of strongly ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell.

The cells did not show any measurable damage or produce extra reactive oxygen species after absorbing the plastic particles. However, all three sorts of particles interact with the cells' nuclei.

University of Maryland researchers used microscopic roundworms as a model to investigate how dsRNA molecules naturally enter cells and influence many future generations. The team discovered ...