What is a desmoid tumor? A desmoid tumor is a rare fibrous growth that can start in the arms, legs, or torso (body). They most commonly grow in the abdomen (belly). These tumors start in connective ...

Bernd Kasper, MD, PhD, provides an overview of the phase 3 DeFi trial of nirogacestat for the treatment of patients with progressing desmoid tumors.

Bernd Kasper, MD, PhD, discusses the key efficacy results from the updated analysis of the phase 3 DeFi trial of nirogacestat in desmoid tumors.

Ogsiveo (nirogacestat) has been cleared as an oral, first-line therapy for adult patients with progressing desmoid tumours who require systemic treatment. Desmoid tumours are not malignant but can ...

The results of the DeFi trial of nirogacestat in 142 adults with progressing desmoid tumours showed a significant 71% improvement with the drug on progression-free survival (PFS) compared to ...