The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

Additionally, HDAC2 levels showed an inverse correlation with kynurenine concentrations, supporting its role in RCC pathophysiology. AC, acetylation; HDAC2, histone deacetylase 2; HIF-α, ...

Figure 2: Dnmt1 686–812 represses transcription in a TSA-sensitive manner and has the ability to interact with the HDAC1 deacetylase. Figure 3: The Dnmt1-interacting region of HDAC1 associates ...

Eight months after announcing the $18.5 million first tranche of its series A, Augustine Therapeutics has closed the oversubscribed round at $85 million and is now ready to begin clinical development ...