STAG2 protein mutations and associated spatial alteration of DNA structure can contribute to development of leukemia
Cohesin contains two very similar subunits, STAG1 or STAG2. In myeloid leukemias, mutations in the cohesin subunit STAG2 are ...
Nature3y
Mitosis and Cell Division
Like cohesin, condensin is an elongated complex of several proteins that binds and encircles DNA. In contrast to cohesin, which binds two sister chromatids together, condensin is thought to bind a ...
Researchers reveal structure and assembly mechanism of unique module in cellulosome
The non-catalytic scaffoldins contain multiple tandem cohesin modules, whereas the cellulosomal enzymes are equipped with ...