The administration of chemotherapeutic drugs at maximum tolerated doses (MTDs) often induces dose-limiting toxicity in rapidly dividing tissues (intestines, bone marrow, and skin), and so patients ...

Race Oncology Ltd (ASX:RAC) has been approved for its Phase One trial of its chemotherapeutic candidate RC220 to treat people ...

Patients with metastatic or unresectable gastric cancer are usually given 5-fluorouracil (5-FU) and platinum-based chemotherapy, but patients with advance disease usually have a poor prognosis. The ...

Some cytotoxic anticancer drugs may boost an immunogenic molecular signal of apoptosis. Why did anthracyclines have this property, whereas many other chemotherapeutic agents did not? It appears ...

However, systemic chemotherapy can lead to significant adverse effects and limited tumour targeting. Bioactive glasses are clinically used for repairing small bone defects however these materials have ...

An international research team has now discovered a mechanism that opens up new treatment strategies for tumours in which conventional chemotherapeutic agents have reached their limits.