研究人员从常见的姜、蒜、芦荟和柠檬中提取出了植物源纳米颗粒（PNP），并发现其包含Nano10和ELN两种不同类型。体外和体内实验均表明，PNP能够被肠道细菌摄取。在众多的肠道细菌中，Lachnospiraceae、Bacteroidaceae等细菌家族在摄取PNP的过程中表现得尤为活跃，是主要的摄取菌。而且，PNP的摄取效率并非一成不变，它会受到PNP类型、植物来源以及肠道微环境等多种因素的影响 ...

TEV PD-L1 有助于 αPD-1 治疗耐药； UBE4A 介导的 PD-L1 泛素化诱导细胞外囊泡对 PD-L1 的分选； 来自肿瘤细胞的 MFGE8 通过激活自身的 α v 整合素信号上调 ...

植物纳米颗粒通过塑造人类共生微生物群代谢物增强抗 PD-L1 疗效的研究解读 美国路易斯维尔大学医学院布朗癌症中心的研究人员在《Nature Communications》期刊上发表了题为 “Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites” 的论文。

Researchers, led by the University of Melbourne's Professor Laura Mackay, a Laboratory Head and Immunology Theme Leader at ...

今日，宜联生物宣布，公司与阿斯利康建立临床研究合作，共同探索YL201（靶向B7H3的抗体偶联药物）与度伐利尤单抗（抗PD-L1免疫检查点抑制剂 ...

In combination with fluoropyrimidine- and platinum-containing chemotherapy as first-line treatment for unresectable locally advanced or metastatic gastric or gastroesophageal junction (G/GEJ) ...

Serplulimab is the world's first anti-PD-1 monoclonal antibody (mAb) approved for first-line treatment of ES-SCLC Serplulimab is the first and only anti-PD-1 mAb approved in the European Union (EU) ...

Priya Hays, Hays Documentation Specialists, discusses innovations and advancements in the development of personalized cancer ...

Tom Equels, CEO of AIM ImmunoTech and Professor Casper H.J. van Eijck, MD, PhD, Pancreato-biliary Surgeon at Erasmus MC, discuss the Phase 1b/2 ...