A person with an addiction uses a substance, or engages in a behavior, for which the rewarding effects provide a compelling incentive to repeat the activity, despite detrimental consequences.

Substance use disorder is a health condition involving compulsive substance use. It can occur with prescription or nonprescription drugs. It can also range from mild to severe. Substance use ...

The Substance first dazzled audiences in May 2024 when it premiered at the Cannes Film Festival and secured Fargeat an award for Best Screenplay. Following Demi Moore as Elisabeth, The Substance ...