Purpose: The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, drug interactions, and role in therapy of vildagliptin for the treatment of type 2 diabetes mellitus were reviewed.

In clinical trials of patients with type 2 diabetes mellitus, vildagliptin has been shown to reduce HbA 1c, fasting plasma glucose levels, prandial glucose levels, and prandial glucagon secretion ...