Small molecules have critical roles at all levels of biological complexity and yet remain orphans of the central dogma. Chemical biologists, working with small molecules, expand our understanding ...

Researchers at Charles River have developed a series of small molecules that target the ATM kinase and have shown promise for the treatment of Huntington’s disease in preclinical studies In ...

Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and association with certain diseases, such as inflammatory bowel disease (IBD) or colorectal cancer ...