Nature4 年
Glycan-masked Engineered Outer Domains of HIV-1 GP120 and Their Use: Collaborative and ...
The VRC01-class of potent, broadly neutralizing antibodies (bnAbs) targets the conserved CD4-binding site (CD4bs) of HIV-1 Env which has been a major target of HIV-vaccine design. The current best ...
Nature4 年
N6, A Novel, Broad, Highly Potent HIV-specific Antibody
This allows N6 to tolerate changes in the HIV envelope, including the attachment of sugars in the V5 region, a major mechanism by which HIV develops resistance to other VRC01-class antibodies.N6 ...