Ulcerative colitis is a type of chronic inflammatory bowel disease that causes painful ulcers and irritation in the large intestine. In North America alone, it is estimated to affect more than ...

Evidence is accumulating that both genetic and environmental factors contribute to ulcerative colitis. The most consistent genetic associations have been shown for the MHC locus HLA Class II ...

Ulceration and denudation seemed to these authors to be the prominent gross pathological features in the ileum involved as a result of extension of chronic ulcerative colitis. Although Cave 20 ...