A new study published in Advanced Science has revealed how curcumin, a bioactive compound found in Curcuma aromatica (Yujin), ...

Figure 1: Contribution of wild-type (WT), Ptpn11-mutant or Fgfr1-mutant ES cells to the developing E10.5 embryo. Figure 4: Development of both the limb buds and the branchial arches is impaired in ...

A new study published in Advanced Science has revealed how curcumin, a bioactive compound found in Curcuma aromatica (Yujin), ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

These motifs have been categorized as (i) phosphorylation-based substrate motifs (that is, motifs that are recognized by serine/threonine/tyrosine kinases or phosphatases and (ii) phosphorylation ...

Kinases, enzymes that phosphorylate proteins, generally control the amplitude of a signal response, whereas phosphatases, enzymes that dephopshorylate proteins, are thought to be important for ...

in individuals who are deficient in the tyrosine phosphatase non-receptor type 2 (PTPN2) protein. Since its emergence at the end of 2019, SARS-CoV-2, which is the virus that causes the coronavirus ...

Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...

The acquisition bolsters Boehringer's immuno-oncology pipeline with Nerio's new PTPN2/N1 [protein tyrosine phosphatase ...

Tyligand Bioscience Ltd. has prepared and tested tyrosine-protein phosphatase non-receptor type 11 (PTPN11; PTP-2C; SHP-2) inhibitors reported to be useful for the treatment of cancer.