The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling pathways is a current focus of the lab. The conformational activation of Src kinase ...

Factors found to be amplified in human tumors are indicated in green and those found to be frequently lost are indicated in red. Black lines indicate direct activation (arrowheads) or inhibition ...

1). The phosphorylation of the biotin-tagged generic peptide is initiated by the addition of ATP in the presence of the tyrosine kinase (step 1) and stopped by the addition of a mix containing the ...

This is a definition of a possible Hy's law case ... No writing assistance was utilized in the production of this manuscript. Tyrosine kinase inhibitors (TKIs) are used for the targeted treatment ...