We applied the miRCURY LNA microarray platform to generate miRNA expression profiles of breast cancer tissue and normal adjacent breast tissue to identify possible new biomarkers for breast cancer 9.

Frozen tumor tissue is indispensable for microarray experiments because the rapid fixation method ensures that the RNA quality remains optimal, with the result that subtle alterations in levels of ...

But this method, widely used for tumor analysis, has shortcomings, including potential sample loss during core retrieval due to variations in tissue depth and quality, and low feature density due to ...

The biggest news these days in tissue microarrays (TMAs) may be that this former "next big thing" has become a standard tool for molecular profiling of disease. Some 682 papers have been published on ...

Tissue microarrays are cheaper and faster than conventional ... using immunohistochemistry (the Reporting Recommendations for Tumor Marker Prognostic Studies guidelines) and these should be ...

By identifying which genes in the cancer cells are working ... The first step in using a microarray is to collect healthy and cancerous tissue samples from the patient. This way, doctors can ...

The clinical relevance of PDK1 Y163 phosphorylation was further established through immunohistochemical staining of tumor tissue microarrays, showing that higher levels of this phosphorylation ...

Our core constructs Tissue Microarrays using human or animal model tissues ... Supported by the Dan L Duncan Comprehensive Cancer Center, human tissue banking takes place routinely at Baylor St.