Troponin is shown in red (subunits not distinguished). Upon binding calcium, troponin moves tropomyosin away from the myosin-binding sites on actin (bottom), effectively unblocking it. Modified ...
Interested parties may access the live webcast of the fireside chat by visiting the Investors & Media section of the Cytokinetics website at https://www.cytokinetics.com. The webcast replay will be ...
a novel fast skeletal muscle troponin activator, aficamten, a novel cardiac myosin inhibitor, and CK-3772271, a novel cardiac myosin inhibitor. The company was founded by Ronald D. Vale ...